Nicotinamide adenine nucleotide (NAD+)
It is required for over 500 enzymatic reactions and plays key roles in the regulation of almost all major biological processes (Ansari and Raghava, 2010). Above all, it may allow us to lead healthier and longer lives. NAD+ levels steadily fall as we age, leading to a decline in the function of cells and organs. By raising NAD+, NAD+ boosters can have profound effects on the health and survival of mammals. Increases in NAD+ promote cognitive and sensory function, gluconeogenesis in the liver, lipogenesis in adipose tissue, insulin secretion in the pancreas, and insulin sensitivity in muscle. NAD+ also promotes endothelial cell proliferation and protects against cardio- and cerebrovascular disease. NAD regulates immune function and inflammation and, protects against acute injury in the kidney. A decline in NAD+ during aging is believed to be a major cause of disease and disability, such as hearing and vision loss, as well as cognitive and motor dysfunction, immune deficiencies, auto-immunity, and dysregulation of the inflammatory response leading to arthritis, metabolic dysfunction, and cardiovascular disease. In mouse models, NAD+ boosters prevent or treat a variety of different diseases, prompting a search for NAD+ boosters that are safe and effective as drugs to treat both rare and common diseases, and potentially aging itself.
Primary effects of Selank
Reduces anxiety and stress: Selank has been shown to reduce generalized anxiety and stress without the sedative side effects or potential for dependence and withdrawal associated with traditional benzodiazepine medications. It helps regulate brain to produce a calming effect while maintaining mental clarity.
Enhances cognitive function: As a nootropic, Selank can improve cognitive functions such as memory, learning, attention span, and concentration. It helps reduce mental fatigue and improve mental endurance.
Boosts mood: By regulating neurotransmitters like serotonin and dopamine, Selank can improve mood and relieve symptoms of depression.
Supports the immune system: Derived from the immune-boosting peptide tuftsin, Selank can enhance immune function by affecting cytokines like Interleukin-6 (IL-6). It has also shown promise in fighting viral and microbial infections.
Provides neuroprotection: Studies suggest that Selank may offer neuroprotective benefits, potentially protecting neurons from damage caused by oxidative stress. This has led to research on its possible applications in treating neurodegenerative diseases.
TB-500
TB-500 is a synthetic fraction of the protein thymosin beta-4. The main purpose of this peptide is to promote healing. The healing effects of TB-500 have been observed in tendons, ligaments, muscles, skin, heart, and eyes. T• Up-regulates Actin and forms a ternary complex with actin and profilin.
Increased cells in healing.
Improves cell migration to the cite of the injury
Soft tissue repair - tendon, ligament, muscle sports, and athletic injuries.
Reduces scar tissue.
Significant repair and regenerative properties.
Enlarged muscle growth, muscle tone, and muscular stamina.
WOLVERINE BLEND
TB-500 as mentioned above with BPC-157 which…. accelerates the healing of many different wounds, including tendon-to-bone healing and superior healing of damaged ligaments. Also, BPC seems to protect organs and prevent ulcers of the stomach. This peptide is also shown to decrease pain in damaged areas. Those who suffer from discomfort due to muscle sprains, tears, and damage may benefit from treatment with this peptide. It can also help aid skin burns in healing at a faster rate and increase blood flow to damaged tissues.
Tendon healing.
Decrease pain.
Increase collagen synthesis.
Quicker recovery times post-injury.
Wound and bone healing.
Decrease in inflammation.
Intestinal issues.
Protects the heart.
Reverse opioid tolerance
Enhance GABA neurotransmission.
GHK-CU peptide
As we get older there is an increase in the activity of inflammatory, cancer-promoting, and tissue destructive genes plus a decrease in the activity of regenerative and reparative genes. The human blood tripeptide GHK possesses many positive effects but declines with age. It improves wound healing and tissue regeneration (skin, hair follicles, stomach, and intestinal linings, and boney tissue), increases collagen and glycosaminoglycans, stimulates the synthesis of decorin, increases angiogenesis, and nerve outgrowth, possesses antioxidant and anti-inflammatory effects, and increases cellular stemness and the secretion of trophic factors by mesenchymal stem cells. Recently, GHK has been found to reset genes of diseased cells from patients with cancer or COPD to a more healthy state. Cancer cells reset their programmed cell death system while COPD patients’ cells shut down destructive tissue genes and stimulate repair and remodeling activities.
Combo of GHK-CU/BPC_157/TB-500
helps heal, decrease inflammation and increasing collagen production. Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has a strong affinity for copper(II) and was first isolated from human plasma. The positive effects of GHK-Cu in the body decrease with age; thus, there is an increase in inflammation, harmful activity, and tissue destruction.
CJC-1295
Function: A Growth Hormone-Releasing Hormone (GHRH) analog that stimulates the pituitary gland to produce more natural growth hormone.
Benefit: Enhances lean muscle, fat loss, and recovery while improving sleep and anti-aging effects.
CJC/ipamorelin combo
This combination gives patients an amplified release in growth hormones and encourages growth hormone releasing peptides. This generates the increase in growth hormones by strengthening the pulse of hormones while increasing the number of active cells secreting the growth hormone. As we age the growth hormone declines and we start seeing increased fat, low energy, and decreased muscle mass.
Combining these two decreases body fat, increases muscle mass, improves strength and energy, improves sleep quality, faster fat burning, boosts the immune system and increases mental and physical performance.
Epithalon
(also spelled Epitalon) is a synthetic tetrapeptide, or four-amino-acid chain, that was developed to mimic the effects of epithalamin, a natural polypeptide from the pineal gland. Extensively researched in Russia, it is known for its potential anti-aging effects, primarily due to its ability to increase the activity of the enzyme telomerase, which helps maintain and lengthen telomere.
Oxytocin
Social and Emotional Well-Being:
Increases feelings of trust, empathy, and social connection
Reduces stress and anxiety
Improves mood and promotes positive social interactions
Enhances sexual arousal and orgasm
Physical Health: Regulates blood pressure and heart rate, Reduces inflammation, Promotes wound healing, and Supports immune function.
Cognitive Function: Enhances memory and learning, Improves decision-making abilities, and Increases motivation and goal-directed behavior.
Other Benefits: Promotes sleep quality, Reduces pain perception, May have anti-cancer effects (limited research), and May help regulate appetite
Oxytocin, often called the "love hormone," plays a crucial role in various aspects of human health and well-being. Here are some of the benefits of oxytocin:
Kisspeptin
Helps regulate the production of sex hormones, potentially reducing symptoms of hormonal imbalances such as hot flashes, mood swings, and infertility.
Increases testosterone levels in men and estrogen levels in women
Kisspeptin-10 is a peptide produced in the hypothalamus that stimulates the release of gonadotropin-releasing hormone (GnRH) which then causes luteinizing hormone (LH) and follicle-stimulating hormone (FSH) to be released from the pituitary gland.
It is used by men who are undergoing testosterone replacement therapy and often used instead of hCG to boost the body’s down testosterone and prevent testicular atrophy.
MOTS-C
16-amino acid peptide encoded by the mitochondrial DNA that helps regulate energy metabolism, insulin sensitivity, and responses to stress.
Metabolic regulation:
MOTs-c helps maintain metabolic homeostasis and is involved in regulating glucose metabolism and insulin sensitivity.
It mimic the benefits of exercise, leading to improved energy levels, exercise capacity, and strength. more energetic and to improve stamina and exercise performance
Aging and disease:
By promoting metabolic flexibility, MOTs-c may have a protective role against age-related decline and diseases, such as diabetes, cardiovascular disease, and osteoporosis. stimulate bone formation.
Thymosin Alpha 1
TA-1 can stimulate the production of immune cells, such as T cells and natural killer cells, enhancing immune function.
It may help improve immune responses in individuals with compromised immune systems
T-cells, in particular, play a critical role in identifying and eliminating infected or damaged cells. Thymosin-alpha 1 helps to activate these T-cells, enhancing their ability to respond to infections and destroy harmful pathogens.
In addition to boosting the activity of T-cells, Thymosin-alpha 1 also helps to regulate immune responses. It ensures that the immune system responds appropriately to threats without overreacting, which is particularly beneficial for individuals with autoimmune disorders. Autoimmune conditions occur when the immune system mistakenly attacks healthy tissues, causing inflammation and damage. Thymosin-alpha 1’s ability to balance immune activity makes it a promising option for managing such conditions while promoting overall immune health.
